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There are some with impeccable credentials on paper — but, in a phrase that is repeatedly used, "failed to shine" at interview. Cambridge has opened up the admissions process to give a clearer picture of the effort that goes into the assessment of each candidate. Churchill College has 39 places in natural sciences and more than direct applicants. As the wind shakes the bare branches of trees outside, the academics discuss an interviewee from a sixth-form college.

The boy is an unusual case — he has won a scholarship to study in the UK after going to school overseas. His home country is a poor one, not known for its education system. One of the women says: He might need a boost in confidence. Next up is a girl from a leading private school, who was strong on paper but stumbled at interview. Partington wonders aloud if tutors can lead a student through an entire degree.

At present, that proportion is Churchill College is a low-rise modernist stack on the edge of the city centre, a series of interlocking brick cubes. It does better on state-school intake than Cambridge as a whole.

This is partly because of its reputation for science, which attracts more state school pupils. In its prospectus , the college is described as having a "friendly, unpretentious social atmosphere".

It is certainly not as physically daunting as some of the grand and ancient buildings in the city centre. The phrase "a good school" comes up repeatedly in the tutors' discussions.

It is used most frequently about private and grammar schools, but also some comprehensive schools, and has a double meaning. It is a school that knows what Cambridge requires, where the school reference is delivered in the terms the university is looking for — the key phrases are ones that emphasise superlative performance compared with their age group: Of one applicant from "a good school", a bemused tutor says: The Sutton Trust , the charity that aims to promote social mobility through education, blames the unequal outcomes between state and private candidates at university level on the poor exam performance of some schools.

She has had "unimaginable teaching difficulties", the tutors hear. Peering at his laptop when her name is announced, Nick Cutler, an admissions tutor at Churchill, says there are "multiple flags". The flags are used to indicate factors such as poverty, or a school that performs very poorly at GCSE. The rapid pace of Cambridge would "kill her", one of the academics says.

There is a despairing consensus around the table that the university cannot repair the gaps in this candidate's knowledge. The candidate's file goes back into the trolley with a clang. Another candidate from a comprehensive school has four contextual data flags by her name.

There is a note too about "teaching difficulties" — a physics teacher who left during the sixth form and a stand-in for chemistry. This is an easier case — her interview scores are high, an eight and a seven out of One of the academics reviews her "flags": There is another girl from a comprehensive school who got an eight at interview, but one academic exclaims: Partington decides to make an offer but to set the hurdle high because of the doubts.

The tutors are divided about this — there is a feeling she has already been stretched thin in a "school that's not great". But they decide this will not be an entrance requirement. The pace is swift, despite the meeting lasting five hours. It is occasionally leavened with a touch of humour, or avuncular kindness. One of the academics, looking at a file photo, sighs: Although a candidate's ethnicity is generally evident from his or her name and the photograph in their file, there is never any overt discussion of race.

Geoff Parks, director of admissions at Cambridge, says later: It's inseparable from socio-economic factors. Cambridge admits a proportion of BME [ethnic minority] students that is above the proportion of the teenage population, [but] with 'low-participation' neighbourhoods we feel we're not meeting a relatively low target. Many people who are first-generation British might also be living in low-participation neighbourhoods. Most of those who apply are interviewed. And the interviews are designed to probe their knowledge deeply.

For natural sciences, the interview has a practical bent, with candidates tackling problems under the gaze of the tutor. One notes approvingly of a candidate who has "done some hard units". Their combination of subjects is also crucial. In a survey of companies carried out by the UK BioIndustry Association in March, 78 percent said they had found it more difficult to raise cash in the previous 12 months.

More than a third of companies trying to raise equity financing failed to do so, while a further 47 percent were not able to obtain all the financing they required. With fewer products in the pipeline and sources of funding drying up, some biotechs are shutting their doors. Others are cutting back to conserve cash and try to hang on until the financing position improves. Companies in the region that have announced staff cuts include Oxford-based Summit Corporation, a zebrafish genomics specialist; Alizyme of Cambridge, which is developing treatments for gastrointestinal diseases; and Silence Therapeutics of London, an siRNA company.

Meanwhile, the pharmaceutical industry worldwide is undergoing the most thorough restructuring and consolidation in its history. And with Pfizer and Wyeth accounting for over 6, jobs in the UK, employees are braced for the job losses that will likely flow from their recent merger.

Accompanying these macroeconomic factors, changes such as the push to interdisciplinary and translational research, as well as the addition of innovation and technology transfer to the research and teaching remits of universities, are changing the nature and practice of academic research and of science-related jobs.

David Rees , senior vice president of medicinal chemistry at Astex Therapeutics, a fragment-based drug discovery specialist based in Cambridge, keeps a keen eye on the recruitment market in the city. Medicinal chemistry has long been a specialty where skills are in short supply, but speaking in March, Rees said there are far fewer job vacancies than 12 months ago.

Whereas Astex and its biotech peers would previously have taken doctoral students straight from university, "It is now possible to recruit people from pharma with lots of experience in chemistry," says Rees. As a consequence, some salaries are falling.

A curious factor is a shift in the perception of risk. Whereas scientists in big pharma previously expected to have secure jobs for life, Rees believes they now have no greater sense of job security than those in biotech. The restructuring of the pharmaceutical industry may be happening under the cover of the global financial crisis, but it was sparked by factors that are particular to the sector. Ann Gales , a partner at the high-level recruitment consultancy Heidrick and Struggles in London, advises that these pressures are reflected in the kinds of people pharma now wants to recruit.

Pharma wants people who are adaptable, and are prepared to collaborate and interact with the public and private sectors," says Gales. There is no less focus on scientific expertise.

Meanwhile, for those embarking on a career in the industry, a first degree in science leaves a wide number of career avenues open.

But there is no doubt that scientists now need to offer commercial skills as well. After 10 years of rising public funding, the UK's science base has never been stronger. One manifestation of this investment is the Diamond Light Source near Oxford, the largest science facility to be built in the UK in the past 40 years. The synchrotron opened just over two years ago and is still in the process of building up its operations. Most recruits are academics, but there is a need for hybrid skills.

And although our scientists have their own projects, the emphasis is on providing a service to our users," says Rayment. While public spending on science is at an all-time high, this has been justified as an investment in the knowledge economy. Inevitably, this has repercussions in terms of the pressures universities are coming under to adopt a more commercial focus in their research, professionalize technology transfer, and collaborate with industry.

Universities such as Oxford, Cambridge, University College London UCL , and Imperial College pride themselves on their commercial edge, and as a movement it is becoming hard for academic researchers to resist, as several recent initiatives highlight. An example is Cambridge University's center specializing in manufacturing technologies for photonics and electronics. This combines research with business development, market analysis, and commercialization skills. Another scheme is bringing industrial "moles" into the heart of academe through Industrial Impact Fellowships.

Researchers from industry join existing projects and programs with a brief to support translation of research. Science Minister Paul Drayson says, "Fellows of this scheme will get to share their experience, skills, and contacts directly with researchers—which is essential to bring innovations from research to market rapidly.

By importing skills from outside, this program is attempting to make up for the perceived deficit of entrepreneurial skills and business knowledge inside universities. But universities are also offering courses in entrepreneurship to their researchers. A leading example is Imperial College's Entrepreneurship Hub, which teaches all science and technology undergraduates entrepreneurship skills and provides training for faculty and researchers in venture creation.

Meet the most impressive students at University of Cambridge. Mambwe took the network down when it became too big for him to handle, but he's in talks with an investment fund looking to acquire it. . Ryan Ammar is the kind of guy who watches "Lord of the Rings" on mute so he can "do all the voices. The science job market in the London–Oxford–Cambridge triangle, after 10 years of rising public investment in the United Kingdom's science. CAMBRIDGE (CBS) – Police are trying to track down a man who was A neighbor's camera caught the man looking into the ground-level.